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Solal – Ubiquinol CoQ10 50mg 60 Capsules


The Ultimate Form of Coenzyme Q10

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This ultimate form of co-enzyme Q10 is unique to SOLAL. Coenzyme Q10 is present in all cells and is known to protect the heart and brain as well as slow down aging markers. Ubiquinol Co Q10 is the active form of coenzyme Q10. It’s 8 times better absorbed than ordinary Co-Q10 and maintains blood Co-Q10 levels 66% better than ordinary Co-Q10 for optimal heart, brain and anti-aging benefits.

Product Indications
Ubiquinol is a stabilised reduced form of co-enzyme Q10 (ubiquinone). Since 2002, scientists have discovered that higher doses and sustained blood levels of co-enzyme Q10 are needed to achieve anti-aging benefits and for optimal protection of the brain and heart. Ubiquinol addresses both these issues since it is 8 times better absorbed than regular co-enzyme Q10 and it results in a 66% increase in continuous blood co-enzyme Q10 levels. This improved form of co-enzyme Q10 not only absorbs better, but also has demonstrated better anti-aging effects compared to conventional co-enzyme Q10. In order for the conventional ubiquinone form of co-enzyme Q10 to be properly utilised, it first must be absorbed then reduced in the body to its active metabolite known as ubiquinol. This is a slow and inefficient process. The optimal way to supplement with co-enzyme Q10 is to ingest it in its ready-to-use ubiquinol form. After years of research, a stabilised ubiquinol has been developed so that it can be swallowed in a capsule for utilisation by cells throughout the body. The ramifications of widespread use of this novel form of co-enzyme Q10 are profound. For the first time, it is possible to achieve the sustained high blood levels of biologically active Ubiquinol Co-enzyme Q10 needed to delay certain manifestations of aging and its related disorders.

Product Composition
Each capsule contains the following as active ingredient:

Ubiquinol 50 mg
Sugar free.

Pharmacological Action
Ubiquinol is the reduction product of co-enzyme Q10 (ubiquinone) and is converted into co-enzyme Q10 after absorption into the body. Studies have shown that ubiquinol has superior absorption compared to co-enzyme Q10, that increases exponentially as the dose increases. This is probably due to the saturation limits attributed to the co-enzyme Q10, while this is not the case with ubiquinol leading to higher levels of absorption. This allows for higher concentration of co-enzyme Q10 in the body allowing for optimal levels to be reached. Those suffering from neurodegenerative disorders, cardiovascular disease, diabetes mellitus and Alzheimer’s display lowered levels of co-enzyme Q10 and would thus benefit from higher levels of co-enzyme Q10 to prevent cellular oxidative damage. Co-enzyme Q10 has been widely studied and has been used in Japan for many decades. Co-enzyme Q10 has been shown to have the following beneficial effects in the body. Cells: Co-enzyme Q10 is an important component of almost every cell of the body and has been found to reverse accelerated abnormal apoptosis of cells involved in the aging process. Co-enzyme Q10 increases the production of energy within the mitochondria of cells and increases oxygen supplies to the mitochondria – the mitochondria contain approximately 50% of the body’s total co-enzyme Q10 content. Co-enzyme Q10 helps to prevent free radical damage to the mitochondria and mitochondrial DNA (including the free radical damage induced by anti-cancer drug doxorubicin). Cardiovascular system: Co-enzyme Q10 stabilizes the heartbeat in arrhythmia patients. Co-enzyme Q10 prevents atherosclerosis in the arteries, by preventing the oxidation of LDL cholesterol. Although it has not received wide publicity, it appears that the co-enzyme Q10-LDL cholesterol ratio is even more important in the prevention of atherosclerosis than the HDL-LDL cholesterol ratio. Co-enzyme Q10 lowers total serum cholesterol levels. Co-enzyme Q10 improves blood circulation and improves the functionality and condition of the heart in the presence of blood clots and cardiomyopathies. A large proportion (approximately 62%) of cardiovascular disease patients are found to be deficient in co-enzyme Q10 and correcting this deficiency through the use of supplemental co-enzyme Q10 is highly effective as a support in the treatment of many cardiovascular disease patients. The heart’s co-enzyme Q10 levels additionally decline with the progression of the aging process. Co-enzyme Q10 improved the condition of 91% of myocardial infarction patients within 30 days of initial co-enzyme Q10 supplementation. Co-enzyme Q10 lowers blood pressure in hypertension patients (39% of hypertension patients are found to be deficient in co-enzyme Q10), by normalizing the body’s sodium-potassium ratio, and via other mechanisms. Co-enzyme Q10 improves the heart’s ability to survive and produce energy in hypoxic situations such as: high altitudes, blocked arteries, decreased flow of oxygenated blood to cardiac muscle, blood with a high fat content, or angina. Co-enzyme Q10 counteracts the toxic effects of ischemia on the brain and myocardial ischemia. Co-enzyme Q10 improves the function of the left ventricle of the heart and normalizes heart function in mitral valve prolapse patients. Co-enzyme Q10 reduces the viscosity of blood in ischemic heart disease patients, assisting to prevent a stroke, and helps to prevent mortality in people who have experienced a stroke. Digestive system: Co-enzyme Q10 facilitates the elimination of candida albicans. Co-enzyme Q10 protects the lining of the stomach and alleviates peptic and duodenal ulcers. Excretory system: Co-enzyme Q10 concentrates in the kidneys and co-enzyme Q10 improves the condition of chronic kidney failure patients. Eyes/vision: Co-enzyme Q10 helps to prevent glaucoma and alleviates ophthalmoplegia. Immune system: Co-enzyme Q10 potently enhances the function of macrophages and phagocytes, and increases the body’s resistance to viruses. Co-enzyme Q10 alleviates allergies and people with severe allergies almost always exhibit lower-than-normal blood levels of co-enzyme Q10. Co-enzyme Q10 can double the body’s level of protective antibodies. Metabolism: Co-enzyme Q10 functions as an anti-oxidant. Co-enzyme Q10 improves athletic performance by increasing the body’s production of energy via adenosine triphosphate (ATP). Co-enzyme Q10 increases energy levels in some chronic fatigue syndrome (CFS) patients, but generally only in those CFS patients who are already deficient in co-enzyme Q10 (approximately 70-75% of CFS patients). Supplemental co-enzyme Q10 alleviates the impaired aerobic function that is associated with fatigue and increases energy levels in persons suffering from general fatigue. Co-enzyme Q10 can alleviate diabetes mellitus: Co-enzyme Q10 reduces blood glucose levels by at least 20% in 36% of diabetes mellitus patients. Many of the complications associated with diabetes mellitus are exacerbated in the presence of co-enzyme Q10 deficiency. Co-enzyme Q10 decreases insulin resistance and prevents the build-up of excessive serum levels of ketones. Co-enzyme Q10 is involved in the conversion of carbohydrates into energy, by increasing the body’s production of adenosine triphosphate (ATP). Supplemental co-enzyme Q10 increases energy in both sedentary individuals and in athletes. People using supplemental co-enzyme Q10 generally report an increase in their subjective feelings of energy. Co-enzyme Q10 is integral to the electron transport system (ETS). Co-enzyme Q10 improves performance during exercise, improves the VO2 max of people who exercise and helps to prevent the damage to muscles that can occur as a result of intensive exercise or endurance exercise. Supplemental co-enzyme Q10 reduces the extent of damage caused to the muscles by intensive exercise. People afflicted with obesity are often deficient in co-enzyme Q10 – supplementation accelerates weight loss. Muscular dystrophy patients are usually found to be deficient in co-enzyme Q10 and supplementation often alleviates muscular dystrophy. Nervous system: Co-enzyme Q10 causes improvement on several Alzheimer’s disease evaluation scales. Co-enzyme Q10 helps to prevent the neuron damage that leads to Alzheimer’s disease. Reversal of mental function deterioration has been documented in several studies utilizing supplemental co-enzyme Q10, including documented improvements in mental function in people with genetically confirmed Alzheimer’s disease. Supplemental co-enzyme Q10 significantly increases the survival time of amyotrophic lateral sclerosis (ALS) patients. Supplemental co-enzyme Q10 increases the production of energy within the brain and may retard the aging process within the brain. Supplemental co-enzyme Q10 concentrates in the cerebral cortex and increases the production of energy within the cerebral cortex. Co-enzyme Q10 improves coordination in cerebella ataxia patients and alleviates multiple sclerosis. Co-enzyme Q10 helps to prevent the death of the brain’s neurons that can occur as a result of the hypoxia associated with ischemia. Co-enzyme Q10 helps to prevent the neuron damage that leads to Parkinson’s disease. It may also be useful in the treatment of Parkinson’s disease. Co-enzyme Q10 may alleviate schizophrenia; most schizophrenia patients are found to have abnormally low co-enzyme Q10 levels. Co-enzyme Q10 protects the striatum of the brain from the toxic effects of neurotoxins. Oral health: Co-enzyme Q10 dramatically halts the progression, bleeding and inflammation of gingivitis and periodontal disease and can totally heal the damage already done. The underlying mechanism by which co-enzyme Q10 exerts the above effects on periodontal disease is by improving energy delivery to the cells of the mouth and gums. The cells of these areas have a very high turnover rate and therefore have a higher-than-normal requirement for energy to fuel their replication. Respiratory system: Co-enzyme Q10 alleviates asthma. Co-enzyme Q10 counteracts hypoxia and increases the ability to perform exercise in chronic obstructive pulmonary disease (COPD) patients. Co-enzyme Q10 improves respiratory performance in emphysema patients. Reproductive system: Co-enzyme Q10 alleviates male infertility, by providing energy and increased motility to sperm.

Dosage Directions
Adults and children over 12 years of age: Take 1 capsule twice daily, with or shortly after food.

Product Warnings
Do not exceed recommended dosages unless on the advice of a health care provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Side Effects
Orally, ubiquinol is generally well tolerated. In clinical studies, there have been no reports of significant adverse effects at recommended doses. Ubiquinol can cause gastrointestinal side effects such as nausea, vomiting, diarrhoea, appetite suppression, heartburn, and epigastric discomfort in less than 1% of patients . Some of these adverse effects can be minimized if total daily doses exceeding 100mg are divided and administered two to three times per day. Allergic rash has been reported.
There are no known contraindications.

Product Interactions
Individuals currently being treated with any of the following medications, should not use Ubiquinol Co-Q10 without first talking to their healthcare provider. Blood Pressure Medications: In a study of individuals taking blood pressure medications (including diltiazem, metoprolol, enalapril, and nitrate), co-enzyme Q10 supplementation allowed the individuals to take lower dosages of these drugs. This suggests that co-enzyme Q10 may enhance the effectiveness of certain blood pressure medications. Daunorubicin and Doxorubicin: Co-enzyme Q10 may help to reduce the toxic effects on the heart caused by daunorubicin and doxorubicin, two chemotherapy medications that are commonly used to treat a variety of cancers . However, there is concern that anti-oxidants such as co-enzyme Q10 might protect tumour cells from chemotherapeutic agents that work by inducing oxidative stress, such as the alkylating agents (e.g. cyclophosphamide, Cytoxan) and radiation therapy. Co-enzyme Q10 should only be used in sufferers under the supervision of a knowledgeable medical practitioner. HMG CoA Reductase Inhibitors (Statins): HMG CoA reductase inhibitors can reduce serum ubiquinol levels. They block the synthesis of mevalonic acid, which is a precursor of co-enzyme Q10. Timolol: Co-enzyme Q10 supplementation may reduce the heart-related side effects of timolol drops, a beta-blocker medication used to treat glaucoma, without decreasing the effectiveness of the medication. Warfarin: There have been reports that co-enzyme Q10 may decrease the effectiveness of blood-thinning medications such as warfarin, leading to the need for increased doses. Therefore, given that this medication must be monitored very closely for maintenance of appropriate levels and steady blood thinning, co-enzyme Q10 should only be used with warfarin under careful supervision by a healthcare provider. Other: Medications that can lower the levels of co-enzyme Q10 in the body include statins for cholesterol, fibric acid derivatives for cholesterol (specifically, gemfibrozil), beta-blockers for high blood pressure (such as atenolol, labetolol, metoprolol, and propranolol), and tricyclic antidepressant medications (including amitriptyline, clomipramine, desipramine, imipramine, nortriptyline, and trimipramine). Interactions with Diseases or Conditions: Hypotension, hypertension: Co-enzyme Q10 might lower blood pressure. It can have additive effects with medications used for hypertension; use with caution. Smoking: Cigarette smoking depletes body stores of co-enzyme Q10. Surgery: Co-enzyme Q10 might affect blood pressure. Theoretically, co-enzyme Q10 might interfere with blood pressure control during and after surgical procedures. Patients are advised to discontinue co-enzyme Q10 at least 2-weeks before elective surgical procedures.

Pregnancy & Breastfeeding
Safety in pregnancy and breastfeeding has not been established, do not use.