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Metagenics – SPM Active 60 Softgels


Specialized Pro-resolving Mediators


SPM Active is a revolutionary new nutritional product developed through advanced fractionation technology featuring standardized levels of SPMs (specialized pro-resolving mediators) found in fish oil.

The body’s immune response helps keep tissues healthy and plays a role in repairing tissue that may have been affected by over exercising or other challenges. When tissues in the body are challenged, the body reacts by developing a tailored immune response. This includes recruiting immune cells, clearing cellular debris of affected tissues, resuming normal immune activity, and maintaining tissue health

Leading-edge science in the resolution of the immune response Groundbreaking research has led to the discovery that the body utilizes omega-3 fatty acids, mainly EPA and DHA , to form SPMs (specialized pro-resolving mediators) to support resolution (i.e., completion) of the body’s natural immune response. Sometimes factors such as aging or a person’s health status can interfere with sufficient production of SPMs in the body from their normal dietary sources, EPA and DHA

SPM Active: Targeted support for the immune response SPM supplementation may provide a targeted, effective approach to supporting tissue health and the natural immune response. That’s why Metagenics introduced SPM Active, an exclusive, standardized SPM formula derived from omega-3 fatty acids. Extensive research suggests that the SPMs found in SPM Active (17-HDHA and 18- HEPE) may promote the body’s natural resolution of the immune response.

Serving Size: 2 Softgels
Ingredient Amount Daily Value
Calories 5
Calories from Fat 5
Total Fat 0.5 g 1%*
Cholesterol 5 mg 2%*
Fractionated Lipid Concentrate†, SPM content standardized to 250 mg **
18-hydroxy-eicosapentaenoic acid (18-HEPE)
17-hydroxy-docosahexaenoic acid (17-HDHA)
Ingredients: Concentrated fish oil [(anchovy and sardine oil, and mixed tocopherols (antioxidant)], softgel shell (gelatin, glycerin, water, pectin, and sorbitol), and lemon oil.
Contains: Fish (anchovy and sardine).

Directions: Take two softgels once daily or as directed by your healthcare practitioner.

This product is gluten free.

Caution: If pregnant, nursing, or taking nutritional supplements or medications, consult your healthcare practitioner before use. Keep out of the reach of children.

Storage: Keep tightly closed in a cool, dry place.

Do not use if safety seal is missing or broken.

†Patent pending.


Certain persons, considered experts, may disagree with one or more of the foregoing statements, but the same are deemed, nevertheless, to be based on sound and reliable authority. No such statements shall be construed as a claim or representation as to Amipro products, that they are offered for the diagnosis, cure, mitigation, treatment or prevention of any disease.


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