Description
Genologix – Phosphatidyl Serine
What Is It and What It’s Promoted For
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Source & Format: This is a 500 mg per day dietary supplement made from soy lecithin and offered in vegan, gluten‑free capsules by Genologix, a South African brand focused on cognitive health and stress support
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Stated Benefits: Genologix promotes improved memory, attention, focus, processing speed, and better cognitive health, including support for stress and cortisol regulation
✅ Summary Table
| Aspect | Details |
|---|---|
| Brand & Source | Genologix, South Africa, 500 mg PS, vegan‑friendly, soy‑derived |
| Dose | 500 mg/day (2 capsules); higher than typical clinical range |
| Claims | Supports memory, focus, processing speed, stress/cortisol regulation |
| Clinical Evidence | Benefit shown in 300–800 mg/day trials for age‑related cognitive decline; enhances neurotransmission and cellular integrity |
| Tolerability | Generally well tolerated; mild side effects possible at high dose |
| Precautions | Consult healthcare provider if pregnant, breastfeeding, or on medications like anticholinergics |
Recommendations Before Use
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Consult your healthcare provider, especially if pregnant, breastfeeding, under 18, or taking prescription medication.
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Start at lower dose, if advised—many safe regimens begin with 100–300 mg daily.
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Monitor for side effects, particularly when using higher 500 mg dose.
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Source awareness: As Genologix claims third-party testing and uses recycled glass packaging, but always check for certification or batch testing if available in South Africa.
Final Thoughts
Genologix Phosphatidyl‑Serine offers a high-dose, plant‑based supplement aimed at enhancing cognition and reducing stress-related cortisol response. Its dosage aligns with therapeutic ranges seen in clinical research, though its strength is above commonly recommended daily amounts. While PS is generally considered safe, especially for healthy adults, those with medical conditions, medication use, or sensitive populations should discuss suitability with a healthcare professional.
Would you like help comparing it against other PS brands or guidance on dosing strategies or diet-based sources of PS?
✅ Top Benefits of Phosphatidylserine
1. Cognitive Enhancement
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Improves memory recall and information retention, especially in aging adults.
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Helps with learning speed, focus, and processing capacity.
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Supports brain function in conditions like age-related cognitive decline and possibly early Alzheimer’s disease.
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Shown to reverse or slow memory deterioration in some elderly populations (clinical trials used 300–800 mg/day).
2. Stress Reduction & Cortisol Modulation
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Helps regulate cortisol levels, the body’s primary stress hormone.
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May reduce stress-related symptoms such as mental fatigue, irritability, and sleep disruption.
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Shown in studies to help reduce exercise-induced stress and chronic psychological stress in high-performing individuals.
3. Better Sleep Quality
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Indirect benefit via cortisol control—lower evening cortisol can promote deeper, more restful sleep.
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Some users report improvements in sleep onset and reduced nighttime waking.
4. Brain Cell Health & Communication
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Maintains integrity of neural cell membranes, improving signal transmission between brain cells.
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Supports neuroplasticity—the brain’s ability to adapt and form new connections, critical for learning and memory.
5. Improved Attention & Focus
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Especially helpful in people with ADHD-like symptoms or mental fog.
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May enhance sustained attention, reaction time, and executive function (i.e., planning and decision-making).
Bonus: Research-Based Observations
| Function | Evidence Level | Summary |
|---|---|---|
| Memory improvement | ✅ Strong (esp. age-related) | Multiple trials show benefit in seniors with mild cognitive impairment. |
| Cortisol control | ✅ Moderate | Measured reduction in stress hormones during stress protocols. |
| Cognitive aging support | ✅ Moderate-Strong | Slows cognitive decline in aging brain. |
| Sleep & mood | ⚠️ Anecdotal–Moderate | Some users report better sleep and mood with regular use. |
| ADHD support | ⚠️ Emerging | Early studies show promise, particularly in children (low-dose trials). |
Who Might Benefit Most?
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Adults 50+ with mild cognitive decline or memory loss.
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Students and professionals seeking improved focus, clarity, and processing.
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Athletes or high-stress individuals looking to lower cortisol and improve recovery.
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People with brain fog, stress-related fatigue, or poor concentration.
The contents of the Knysna Health website shall not be regarded as medical advice, or a basis from which to make medical decisions. The use of information found on this site is completely your responsibility and at your own risk. Our recommendation is that if you have health concerns that you feel unsure about how to deal with, that you contact your trusted health professional for personalized advice.





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