Description
Phytopure Apigeninx 60 Vegicaps
Phytopure® Apigenin is a high-quality liposomal supplement designed to support brain health, calmness, and restorative sleep, while also promoting healthy ageing.
Key Features & Benefits:
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Contains liposomal apigenin (100 mg per capsule, delivering ~50 mg of active apigenin), for enhanced absorption and bioavailability.
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Acts as a powerful antioxidant and anti-inflammatory agent, helping to protect neurons from oxidative stress and neuroinflammation — two factors that contribute to cognitive decline.
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Modulates GABAα_\alpha receptors in the brain, which helps promote relaxation and better-quality sleep.
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Supports long-term brain resilience and healthy ageing by maintaining neuronal integrity and reducing stress at a cellular level.
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Uses liposomal delivery technology, where each apigenin molecule is encapsulated in a phospholipid layer to protect it from degradation in the digestive tract and improve uptake into cells.
Ingredients:
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Liposomal Apigenin – 100 mg per capsule
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Provides 50 mg of Apigenin
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Capsule is vegan (“vegicaps”)
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Sugar-free, gluten-free, no artificial additives
Benefits:
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Neuroprotective / Brain Health
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Apigenin has strong antioxidant effects, helping to neutralize reactive oxygen species (ROS) that can damage neurons.
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It reduces neuroinflammation by downregulating inflammatory pathways (e.g., NF-κB), protecting brain cells over time.
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Supports long-term cognitive resilience and healthy ageing.
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Calm / Anxiety Reduction
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Apigenin interacts with GABAα_α receptors (a major inhibitory pathway in the brain), which helps promote a relaxing effect.
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This may help reduce mild anxiety or restlessness, without the strong sedative effects of some pharmaceuticals.
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Improved Sleep Quality
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Because of its GABAergic modulation, apigenin can support restorative sleep, helping you fall asleep more easily and stay in deeper sleep.
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Unlike some sleep aids, it’s not strongly sedative — more about promoting natural calmness.
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Healthy Ageing / Cellular Protection
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By reducing oxidative stress and inflammation, apigenin may protect brain cells and mitochondria, supporting healthy ageing.
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There is also some evidence (from animal studies) that apigenin can influence NAD+ metabolism (a molecule involved in ageing), potentially giving it anti-ageing effects.
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Good Bioavailability (Liposomal Delivery)
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The Phytopure formulation is liposomal, meaning each apigenin molecule is encapsulated in a phospholipid “bubble.” This protects it from breakdown in the gut and enhances uptake into cells, increasing effectiveness.
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Better absorption means you may need lower doses to get good effects, compared to non-liposomal forms.
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Safe & Well-Tolerated
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According to the manufacturer, it is generally well tolerated with possible mild drowsiness for some people.
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It’s plant-derived and more “natural” than many synthetic sleep or neuro supplements.
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Mechanism of Action:
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Apigenin is a natural flavonoid found in plants like chamomile, parsley, citrus, and celery.
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It neutralises reactive oxygen species (ROS), helping protect brain cells from oxidative damage.
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It downregulates inflammatory pathways (e.g. NF-κB), reducing neuroinflammation.
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Through its interaction with GABAα_\alpha receptors, it gently promotes relaxation without strong sedative effects.
The contents of the Knysna Health website shall not be regarded as medical advice, or a basis from which to make medical decisions. The use of information found on this site is completely your responsibility and at your own risk. Our recommendation is that if you have health concerns that you feel unsure about how to deal with, that you contact your trusted health professional for personalized advice.




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