Willow – P5P (Pyridoxal 5 Phosphate) 50MG (60)

Description

Willow – P5P (Pyridoxal 5 Phosphate) 50MG (60)

What is P5P?

• Pyridoxal‑5‑phosphate (P5P) is the active coenzyme form of vitamin B6—bypassing the need for conversion in the liver—which supports over 100 enzyme reactions in amino acid, carbohydrate, and lipid metabolism, neurotransmitter synthesis, hemoglobin formation, and more

• Commonly used by individuals with liver issues, certain genetic enzyme deficiencies, or on medications that impair B6 conversion

✅ Potential Benefits (50 mg dose)

1. Supports nerve and brain health
   As the active form, P5P supports neurotransmitter production (e.g., dopamine, serotonin, GABA), potentially aiding mood, anxiety, and neurological function

2. May reduce prolactin
   By boosting dopamine, P5P can lower prolactin levels—used by bodybuilders to help prevent gynecomastia and manage hormonal balance

3. Helps with anemia & PMS
   Shows therapeutic benefit in sideroblastic anemia (sometimes with 50 mg) and PMS symptom relief

4. Energy metabolism & hormone balance
   Facilitates conversion of amino acids, fatty acids, glycogen; supports hemoglobin and hormone metabolism .

Dosage

• One tablet of 50 mg daily, often with food .

• Clinical use:

  • Sideroblastic anemia: as low as 50 mg effective

  • General support: many supplement brands supply 25–100 mg; 250 mg/day used safely in short-term studies, but long-term safety unknown

✅ Bottom Line

P5P 50 mg offers a bioactive form of B6 that supports neurotransmitter balance, energy metabolism, and blood health—especially beneficial for those with conversion issues or higher metabolic demand. While generally well‑tolerated at moderate doses, daily intake at or above 50 mg may raise concerns for neuropathy, GI upset, and potential drug interactions. Speak with your healthcare provider to ensure it fits your medical profile, especially if you’re pregnant or on multiple medications.

The contents of the Knysna Health website shall not be regarded as medical advice, or a basis from which to make medical decisions. The use of information found on this site is completely your responsibility and at your own risk. Our recommendation is that if you have health concerns that you feel unsure about how to deal with, that you contact your trusted health professional for personalized advice.