A blend of 3 non-addictive pure herbal extracts (valerian, passion flower and corydalis) to assist with insomnia.
Valerian is a root extract that induces sleep and improves quality of sleep. It also reduces the breakdown of the brain’s natural sleep-inducing neurotransmitter, GABA. Corydalis is a herb that promotes calm and relieves anxiety. Passion flower calms the central nervous system.
Each capsule contains the following active ingredients:
|Passion flower extract||100mg|
Inactive ingredients: Hypromellose (cellulose) vegetarian capsule shell (gelatine free), magnesium stearate and magnesium silicate.
The pharmacological effects of valerian have primarily been attributed to valepotriades. The sesquiterpenes, valerenic acid and kessel glycol, have been shown to cause sedation in animals. Valerenic acid and other constituents of valerian are gamma-aminobutyric acid (GABA) agonists. Valerian constituents may inhibit the enzyme system responsible for the central catabolism of GABA, increasing GABA concentrations and decreasing central nervous system (CNS) activity. Valerian may also bind directly to GABA-A receptors and stimulate the release and reuptake of GABA. Valerian might also affect sleep regulation with activity on adenosine and 5-hydroxytryptamine-1. A naturally occurring alkaloid, dl-Tetrahydropalmatine (dl-THP), present in Corydalis, has been intensively studied for its sedative and hypnotic effects.
It is believed the mechanism and target of action involves the dopaminergic neurotransmission system. Some evidence suggests that the passionflower constituent apigenin binds to central benzodiazepine receptors, possibly causing anti-anxiolytic effects without impairing memory or motor skills.
Take 2 capsules approximately one hour before bedtime. Can be taken with a meal or on an empty stomach.
Not intended for use in children under 12 years of age. The dosage can be increased up to a maximum of 4 capsules, but only under the supervision of a healthcare provider.
Do not use this product if you are hypersensitive (allergic) to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy. Do not exceed recommended dosages unless on the advice of a healthcare practitioner. This medicine has not been evaluated by the Medicines Control Council. This medicine is not intended to diagnose, treat, cure or prevent any disease.
Do not use continually for more than 3 months without consulting your healthcare practitioner.
Do not drive or operate machinery for 8 hours after taking Herbal Sleep™. Alcohol can compound the drowsiness caused by Herbal Sleep™ and should be used with caution.
Surgery: The sedative effect of Herbal Sleep™ might cause additive CNS depression when combined with anaesthesia during surgical procedures. Discontinue Herbal Sleep™ at least 2 weeks before elective surgical procedures.
The following side effects have been reported: dizziness, confusion, sedation, headache and ataxia.
Do not use Herbal Sleep™ if you have a history of kidney or liver disease.
CNS Depressants: Concomitant use with sedatives might increase the risk of excessive sedation and drowsiness. Some CNS depressants are benzodiazepines, pentobarbital, phenobarbital, secobarbital, thiopental, fentanyl, morphine, propofol and others.
Pregnancy and Breastfeeding
Safety during pregnancy and whilst breastfeeding has not been established, do not use.
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