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Solal – Hormone Balance 60 Capsules


A safe and effective alternative to pharmaceutical hormone replacement therapy.


Product Indications
Hormone Balance Natural HRT is a safe and effective alternative to pharmaceutical hormone replacement therapy. Hormone Balance Natural HRT contains a proprietary standardised herbal formula, combining the estrogenic and progestogenic herbs, black cohosh and agnus castus. This provides balanced protection from menopausal and PMS symptoms such as hot flushes, night sweat and mood swings. Hormone Balance Natural HRT also contains ipriflavone, a plant-derived isoflavone, which protects and improves bone mineral density, when used with calcium supplement (such as SOLAL’s Calcium Glycinate, the most bioavailable and effective form of calcium).

Product Composition
Each capsule contains a propriety standardised herbal complex of Agnus castus, Black cohosh, Ipriflavone and Vitamin D3 : Inactive ingredients: Hypromellose (cellulose) vegetarian capsule shell (gelatine free), microcrystalline cellulose, magnesium stearate (vegetarian – flow agent), magnesium silicate, silicon dioxide and colloidal silicon dioxide. Contains plant extracts and natural fillers, with no colourants added – therefore the colour of the capsule contents may vary slightly from batch to batch.
Storage Instructions
Store in a cool dry place below 25°C. Keep out of the reach of children.

Pharmacological Action
Agnus castus is obtained from the berries of the chaste tree. Constituents of agnus castus bind selectively to estrogen receptor beta. The beta receptor predominates in the heart, arteries, veins, bone and bladder. Agnus castus extracts also have agonistic effects at pituitary dopamine (D2) receptors when used in higher doses. This dopaminergic activity inhibits basal and thyrotropin-releasing hormone (TRH)-stimulated prolactin release. In women with hyperprolactinemia, chasteberry seems to suppress prolactin release. This may normalize luteal phase defects in the menstrual cycle. It’s thought that black cohosh might have selective estrogen receptor modulating (SERM) effects and therefore have estrogenic effects in some tissues and anti-estrogenic effects in other tissues. Preliminary research suggests that black cohosh might also act as a partial agonist at serotonin receptors which could also play a potential role in reducing menopausal symptoms. Preliminary clinical evidence also suggests that black cohosh might increase osteoblast activity by increasing levels of bone-specific alkaline phosphatase (bALP), which is a marker of bone formation. Ipriflavone enhances osteoblast function and inhibits bone resorption, mainly by inhibiting recruitment of osteoclasts. Preliminary evidence suggests that ipriflavone prevents bone density loss without suppressing the rate of bone formation. Ipriflavone has no direct estrogenic activity in postmenopausal women, but might potentiate the effects of estrogen on bone, increase the uterotropic activity of estrogen and stimulate estrogen-induced calcitonin secretion. Clinical evidence suggests that using ipriflavone in combination with conjugated estrogens for postmenopausal osteoporosis might allow for use of a lower estrogen dose. Vitamin D plays an important role in increasing the absorption of calcium and preventing osteoporosis.

Dosage Directions
Adult woman: Take 2 capsules daily, after a meal, or as recommended by your healthcare provider. For menopausal symptoms use continuously. For PMS (pre-menstrual syndrome) use for 7-10 days, starting about 5 days before end of menstrual cycle. For bone mineral density protection, use with SOLAL’s Calcium Glycinate. For added menopausal and PMS symptom relief Hormone Balance Natural HRT can be combined with Sol-Oil Omega 3 & 6 and Magnesium Glycinate.

Product Warnings
Hormone Balance Natural HRT contains black cohosh which can in rare cases cause liver problems. If you become unwell or suffer the following symptoms: yellowing eyes/skin, nausea, vomiting, dark urine, abdominal pain, unusual tiredness, then stop immediately and seek medical advice. Hormone Balance Natural HRT should not be used in woman with a history of or suffering from hormone sensitive cancers. Do not exceed recommended dosages unless on the advice of a health care provider. Do not use this product if you are allergic to any of the ingredients. If you are on any medication or suffering from any medical condition, it is advisable to seek medical advice before starting any new medicine, supplement or remedy.

Side Effects
Hormone Balance Natural HRT is generally well tolerated. Side-effects include: allergy, skin reactions, eczema, urticaria, headache, dizziness, breast tenderness, vaginal spotting or bleeding, diarrhoea, nausea, heartburn and vomiting. Rarely causes raise liver enzymes and hepatotoxicity.

Product Interactions
Antipsychotic medicines: It is possible that agnus castus may interfere with the action of dopamine antagonists due to its dopinergic effects. Some of the antipsychotic drugs include: chlorpromazine, clozapine, fluphenazine, haloperidol, olanzapine, perphenazine, prochlorperazine, quetiapine, risperidone, thioridazinel and thiothixene. Contraceptive medicines: Could interfere in the effectiveness of contraceptive drugs due to its hormone modulating activity, use with caution. Estrogens: Could interfere in the effectiveness of hormone replacement therapy as Hormone Balance Natural HRT has its own hormone modulating activity. Cisplatin: Preliminary evidence suggests the black cohash might decrease the effectiveness of cisplatin. Cytochrome P450: Hormone Balance Natural HRT may modestly inhibit P450 2D6, 2C9 and 1A2. Medicines metabolised by P450 2D6, 2C9 and 1A2 include amitriptyline, codeine, desipramine, flecainide, haloperidol, imipramine, metoprolol, ondansetron, paroxetine, risperidone, tramadol, venlafaxine, clozapine, cyclobenzaprine, fluvoxamine, haloperidol, imipramine, mexiletine, olanzapine, pentazocine, propranolol, tacrine, theophylline, zileuton, zolmitriptan, amitriptyline, diazepam, estradiol, tacrine, verapamil, warfarin, zileuton and others. Hepatotoxic medicines: There is concern that black cohosh might be linked to cases of liver failure and autoimmune hepatitis. Taking black cohosh with hepatotoxic medicines may increase the risk of liver damage. Immunosuppressants: Concurrent use of ipraplavone and immunosuppressant medicines may have additive effects on inhibiting the immune system. Theophylline: Concurrent use of ipriflavone and theophylline can increase serum theophylline levels.

Pregnancy & Breastfeeding
Not to be taken by pregnant and breastfeeding woman.